Opportunities and Challenges in Functional Genomics Research in Osteoporosis: Report From a Workshop Held by the Causes Working Group of the Osteoporosis and Bone Research Academy of the Royal Osteoporosis Society on October 5th 2020

Opportunities and Challenges in Functional Genomics Research in Osteoporosis: Report From a Workshop Held by the Causes Working Group of the Osteoporosis and Bone Research Academy of the Royal Osteoporosis Society on October 5th 2020

The discovery that sclerostin is the faulty protein underlying the uncommon heritable bone mass dysfunction, sclerosteosis, in the end led to growth of anti-sclerostin antibodies as a new therapy for osteoporosis. In the period of giant scale GWAS, many further genetic alerts related to bone mass and associated traits have since been reported. However, how greatest to interrogate these alerts in order to determine the underlying gene chargeable for these genetic associations, a prerequisite for figuring out drug targets for additional remedies, stays a problem.

These databases present details about potential molecular mediators corresponding to mRNA expression, protein expression, and DNA methylation ranges, which might be interrogated to map genetic alerts to particular genes based mostly on identification of causal pathways between the genetic sign and the phenotype being studied. Functional analysis of potential causative genes has been facilitated by characterization of the “osteocyte signature”, by broad phenotyping of knockout mice with deletions of over 7,000 genes, in which extra detailed skeletal phenotyping is presently being undertaken, and by growth of zebrafish as a extremely environment friendly further in vivo mannequin for useful research of the skeleton.

Looking to the future, this increasing repertoire of instruments affords the hope of precisely defining the main genetic alerts which contribute to osteoporosis. This could in flip result in the identification of further therapeutic targets, and in the end new remedies for osteoporosis. The sources obtainable for supporting useful genomics analysis continues to increase, exemplified by “multi-omics” database sources, with improved availability of datasets derived from bone tissues.

On the street to sensible biomaterials for bone analysis: definitions, ideas, advances, and outlook

The demand for biomaterials that promote the restore, substitute, or restoration of exhausting and delicate tissues continues to develop as the inhabitants ages. Traditionally, sensible biomaterials have been thought as people who reply to stimuli. However, the steady evolution of the subject warrants a contemporary take a look at the idea of smartness of biomaterials. This evaluation presents a redefinition of the time period “Smart Biomaterial” and discusses latest advances in and functions of sensible biomaterials for exhausting tissue restoration and regeneration.

To make clear the use of the time period “sensible biomaterials”, we suggest 4 levels of smartness in accordance with the stage of interplay of the biomaterials with the bio-environment and the organic/mobile responses they elicit, defining these supplies as inert, lively, responsive, and autonomous. Then, we current an up-to-date survey of functions of sensible biomaterials for exhausting tissues, based mostly on the supplies’ responses (exterior and inside stimuli) and their use as immune-modulatory biomaterials. Finally, we talk about the limitations and obstacles to the translation from primary analysis (bench) to medical utilization that’s required for the growth of clinically related functions of these applied sciences.

Breast most cancers generally metastasizes to bone, ensuing in osteolytic lesions and poor affected person high quality of life. The bone extracellular matrix (ECM) performs a crucial function in most cancers cell metastasis by means of the bodily and biochemical cues it supplies to help mobile crosstalk. Current two-dimensional in-vitro fashions lack the spatial and biochemical complexities of the native ECM and don’t totally recapitulate crosstalk that happens between the tumor and endogenous stromal cells. Engineered fashions corresponding to bone-on-a-chip, extramedullary bone, and bioreactors are presently used to mannequin mobile crosstalk and bone-tumor cell interactions, however fall quick of offering a bone-biomimetic microenvironment.

Three-dimensional bioprinting permits for the deposition of biocompatible supplies and dwelling cells in complicated architectures, in addition to supplies a means to raised replicate organic tissue niches in-vitro. In most cancers analysis particularly, 3D constructs have been instrumental in seminal work modeling most cancers cell dissemination to bone and bone-tumor cell crosstalk in the skeleton. Furthermore, the use of biocompatible supplies, corresponding to hydroxyapatite, permits for printing of bone-like microenvironments with the skill to be implanted and studied in in-vivo animal fashions. Moreover, the use of bioprinted fashions may drive the growth of novel most cancers therapies and drug supply automobiles.

Bayesian methods in palliative care research: cancer-induced bone pain.

Horseradish Peroxidase-Crosslinked Calcium-Containing Silk Fibroin Hydrogels as Artificial Matrices for Bone Cancer Research

Hydrogels, being succesful of mimicking the extracellular matrix composition of tissues, are vastly used as synthetic matrices in tissue engineering functions. In this research, the era of horseradish peroxidase (HRP)-crosslinked silk fibroin (SF) hydrogels, utilizing calcium peroxide as oxidizer is reported. The proposed quick forming calcium-containing SF hydrogels spontaneously endure SF conformational adjustments from random coil to β-sheet throughout time, exhibiting ionic, and pH stimuli responsiveness. In vitro response reveals calcium-containing SF hydrogels’ encapsulation properties and their skill to advertise SaOs-2 tumor cells dying after 10 days of culturing, upon full β-sheet conformation transition.

Bone sialoprotein 2
AP87916 1mg
EUR 2640

Bone sialoprotein 2
AP87966 1mg
EUR 2640

Bone sialoprotein 2
AP88388 1mg
EUR 2640

Bone sialoprotein 2
AP78800 1mg
EUR 2640

Bone Sialoprotein Antibody
E19-7738-1 50ug/50ul
EUR 145
Description: Available in various conjugation types.

Bone Sialoprotein Antibody
E19-7738-2 100ug/100ul
EUR 225
Description: Available in various conjugation types.

Bone Sialoprotein Antibody
DF7738 200ul
EUR 420

Bone Sialoprotein Antibody
DF7738-100ul 100ul
EUR 280

Bone Sialoprotein Antibody
DF7738-200ul 200ul
EUR 350

Bone Sialoprotein Antibody
45125-100ul 100ul
EUR 302.4

Bone Sialoprotein Antibody
45125-50ul 50ul
EUR 224.4

Bone Sialoprotein Antibody
ABD7738 100 ug
EUR 525.6

Active Bone Sialoprotein (BSP)
APB092Hu61 10ug
EUR 301

Bone Sialoprotein (BSP) Antibody
20-abx175605
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  • 1 mg
  • 200 ug

Bone Sialoprotein (BSP) Antibody
20-abx175606
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  • 1 mg
  • 200 ug

Bone Sialoprotein (BSP) Antibody
20-abx175607
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  • 1 mg
  • 200 ug

Bone Sialoprotein (BSP) Antibody
20-abx171455
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  • 1 mg
  • 200 ug

Bone Sialoprotein (BSP) Antibody
abx175605-1096tests 10 × 96 tests Ask for price

Bone Sialoprotein (BSP) Antibody
abx175605-596tests 5 × 96 tests Ask for price

Bone Sialoprotein (BSP) Antibody
abx175605-96tests 96 tests
EUR 712.5

Bone Sialoprotein (BSP) Antibody
abx175606-1096tests 10 × 96 tests
EUR 725

Bone Sialoprotein (BSP) Antibody
abx175606-596tests 5 × 96 tests
EUR 337.5

Bone Sialoprotein (BSP) Antibody
abx175606-96tests 96 tests
EUR 262.5

Bone Sialoprotein (BSP) Antibody
abx171455-1ml 1 ml
EUR 750

Bone Sialoprotein (IBSP) Antibody
20-abx216122
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  • 100 ug
  • 50 ug

Eukaryotic Bone Sialoprotein (BSP)
EPB092Hu61 10ug
EUR 261

Eukaryotic Bone Sialoprotein (BSP)
EPB092Hu62 10ug
EUR 263

Eukaryotic Bone Sialoprotein (BSP)
EPB092Mu61 10ug
EUR 210

Eukaryotic Bone Sialoprotein (BSP)
RPU58873-100ug 100ug
EUR 705.6

Eukaryotic Bone Sialoprotein (BSP)
RPU58873-1mg 1mg
EUR 3276

Eukaryotic Bone Sialoprotein (BSP)
RPU58873-50ug 50ug
EUR 519.8

Eukaryotic Bone Sialoprotein (BSP)
RPU59089-100ug 100ug
EUR 975.2

Eukaryotic Bone Sialoprotein (BSP)
RPU59089-1mg 1mg
EUR 3814.2

Eukaryotic Bone Sialoprotein (BSP)
RPU59089-50ug 50ug
EUR 609.6

Eukaryotic Bone Sialoprotein (BSP)
RPU59090-100ug 100ug
EUR 982.7

Eukaryotic Bone Sialoprotein (BSP)
RPU59090-1mg 1mg
EUR 3843.5

Eukaryotic Bone Sialoprotein (BSP)
RPU59090-50ug 50ug
EUR 614.3

Recombinant Bone Sialoprotein (BSP)
RPU55268-100ug 100ug
EUR 556.6

Recombinant Bone Sialoprotein (BSP)
RPU55268-1mg 1mg
EUR 2467.4

Recombinant Bone Sialoprotein (BSP)
RPU55268-50ug 50ug
EUR 447.7

Recombinant Bone Sialoprotein (BSP)
RPB092Hu01 10ug
EUR 181

Recombinant Bone Sialoprotein (BSP)
4-RPB092Hu01
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  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Bone Sialoprotein expressed in: E.coli

Recombinant Bone Sialoprotein (BSP)
RPB092Mu02 10ug
EUR 140

Rat Bone Sialoprotein ELISA kit
E01A10475 96T
EUR 700
Description: ELISA

Dog Bone Sialoprotein ELISA kit
E08B0392-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Bone Sialoprotein ELISA kit
E08B0392-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Bone Sialoprotein ELISA kit
E08B0392-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Bone Sialoprotein ELISA kit
E07B0392-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Bone Sialoprotein ELISA kit
E07B0392-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Bone Sialoprotein ELISA kit
E07B0392-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Bone Sialoprotein ELISA kit
E02B0392-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Bone Sialoprotein ELISA kit
E02B0392-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Bone Sialoprotein ELISA kit
E02B0392-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bone sialoprotein 2 (IBSP)
1-CSB-EP010945HU(A4)
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  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Bone sialoprotein 2 (IBSP),partial expressed in E.coli

Bone Sialoprotein Blocking Peptide
DF7738-BP 1mg
EUR 234

Goat Bone Sialoprotein ELISA kit
E01A45387 96T
EUR 700
Description: ELISA

Goat Bone Sialoprotein ELISA kit
E06B0392-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Bone Sialoprotein ELISA kit
E06B0392-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Bone Sialoprotein ELISA kit
E06B0392-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Sheep Bone Sialoprotein ELISA kit
E01A97680 96T
EUR 700
Description: ELISA

Mouse Bone Sialoprotein ELISA kit
E03B0392-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bone Sialoprotein ELISA kit
E03B0392-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bone Sialoprotein ELISA kit
E03B0392-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bone Sialoprotein ELISA kit
E01B0392-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bone Sialoprotein ELISA kit
E01B0392-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bone Sialoprotein ELISA kit
E01B0392-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bone Sialoprotein ELISA kit
E01A1713 96T
EUR 700
Description: ELISA

Mouse Bone Sialoprotein ELISA kit
E01A19216 96T
EUR 700
Description: ELISA

Mouse Bone Sialoprotein ELISA Kit
IMSBSPKT each
EUR 718
Description: Mouse Bone Sialoprotein ELISA Kit

Human Bone Sialoprotein ELISA Kit
IHUBSPKT each
EUR 700
Description: Human Bone Sialoprotein ELISA Kit

Canine Bone Sialoprotein ELISA kit
E01A62821 96T
EUR 700
Description: ELISA

Rabbit Bone Sialoprotein ELISA kit
E01A27955 96T
EUR 700
Description: ELISA

Rabbit Bone Sialoprotein ELISA kit
E04B0392-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Bone Sialoprotein ELISA kit
E04B0392-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Bone Sialoprotein ELISA kit
E04B0392-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Bone Sialoprotein ELISA kit
E01A71534 96T
EUR 700
Description: ELISA

Bovine Bone Sialoprotein ELISA kit
E01A80251 96T
EUR 700
Description: ELISA

Monkey Bone Sialoprotein ELISA kit
E09B0392-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Bone Sialoprotein ELISA kit
E09B0392-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Bone Sialoprotein ELISA kit
E09B0392-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Bone Sialoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Bone sialoprotein 2 (IBSP) Antibody
20-abx211839
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  • 100 ul
  • 50 ul

Bone sialoprotein 2 (IBSP) Antibody
20-abx212189
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  • 100 ul
  • 50 ul

Bone Sialoprotein 2 (IBSP) Antibody
20-abx126940
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  • 100 ul
  • 200 ul

Bone Sialoprotein 2 (IBSP) Antibody
abx027806-400ul 400 ul
EUR 627.6

Bone Sialoprotein 2 (IBSP) Antibody
abx027806-80l 80 µl
EUR 343.2

IBSP Antibody / Bone Sialoprotein 2
R30578 100 ug
EUR 356.15
Description: Integrin-binding sialoprotein, also known as Bone sialoprotein and BSP, is a major structural protein of the bone matrix. Bone sialoprotein is a predicted 35KD acidic glycoprotein that undergoes extensive posttranslational modifications and is visualized by western blot at up to 70KD. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. The BSP gene is mapped to 4q22.1.

IBSP Antibody / Bone Sialoprotein 2
R32939 100 ug
EUR 356.15
Description: IBSP (integrin-binding sialoprotein) is also known as BSP. The protein encoded by this gene is a major structural protein of the bone matrix. Bone sialoprotein is an acidic glycoprotein of approximately 70 kD that undergoes extensive posttranslational modifications. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. The BSP gene is mapped to 4q22.1.

Bone Sialoprotein 2 (IBSP) Antibody
abx027806-400l 400 µl
EUR 518.75

Bone Sialoprotein 2 (IBSP) Antibody
abx211839-100l 100 µl
EUR 350

Bone Sialoprotein 2 (IBSP) Antibody
abx211839-50l 50 µl
EUR 250

Bone Sialoprotein 2 (IBSP) Antibody
abx212189-100l 100 µl
EUR 350

Bone Sialoprotein 2 (IBSP) Antibody
abx212189-50l 50 µl
EUR 250

Bone Sialoprotein 2 (IBSP) Antibody
abx376309-96tests 96 tests
EUR 225

Bone Sialoprotein Conjugated Antibody
C45125 100ul
EUR 476.4

Porcine Bone Sialoprotein ELISA kit
E01A54104 96T
EUR 700
Description: ELISA

Chicken Bone Sialoprotein ELISA kit
E01A88977 96T
EUR 700
Description: ELISA

Human Bone Sialoprotein (BSP) Protein
20-abx652149
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Bone Sialoprotein (BSP) Protein
20-abx652699
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Bone Sialoprotein (BSP) Protein
20-abx652700
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Bone Sialoprotein (BSP) Protein
abx652149-5mg 5 mg
EUR 412.5

Mouse Bone Sialoprotein (BSP) Protein
abx652699-5mg 5 mg
EUR 4525

Mouse Bone Sialoprotein (BSP) Protein
abx652700-5mg 5 mg
EUR 337.5

Rat Bone Sialoprotein (BSP) CLIA Kit
abx196761-96tests 96 tests
EUR 990

Rat Bone Sialoprotein (BSP) CLIA Kit
abx196761-100l 100 µl Ask for price

Rat Bone Sialoprotein (BSP) CLIA Kit
abx196761-50l 50 µl
EUR 618.75

Rat BSP(Bone Sialoprotein) ELISA Kit
ELK9503-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat BSP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat BSP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat BSP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat BSP in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat BSP(Bone Sialoprotein) ELISA Kit
ELK9503-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat BSP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat BSP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat BSP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat BSP in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat BSP(Bone Sialoprotein) ELISA Kit
ER0777 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.469 ng/ml

Rat BSP(Bone Sialoprotein) ELISA Kit
EKF58842-48T 48T
EUR 396.9

Rat BSP(Bone Sialoprotein) ELISA Kit
EKF58842-5x96T 5x96T
EUR 2693.25

Rat BSP(Bone Sialoprotein) ELISA Kit
EKF58842-96T 96T
EUR 567

Rat BSP (Bone Sialoprotein) ELISA Kit
EKE62065-5x96T 5x96T
EUR 3124.08

Rat BSP (Bone Sialoprotein) ELISA Kit
EKE62065-96T 96T
EUR 657.7

Pig Bone Sialoprotein (BSP) ELISA Kit
abx361296-96tests 96 tests
EUR 990

Rat Bone Sialoprotein (BSP) ELISA Kit
abx256746-96tests 96 tests
EUR 904.8

Rat Bone Sialoprotein (BSP)  ELISA Kit  
NSL1578r 96 Tests
EUR 498

Rat Bone Sialoprotein(BSP) ELISA Kit
NSL0901r 96 Tests
EUR 498

ELISA Kit for Bone Sialoprotein (BSP)
SEB092Hu 96Т
EUR 665

ELISA Kit for Bone Sialoprotein (BSP)
SEB092Mu 96Т
EUR 684

Rat bone sialoprotein,BSP ELISA Kit
YLA0728RA-48T 48T Ask for price

Rat bone sialoprotein,BSP ELISA Kit
YLA0728RA-96T 96T Ask for price

Rat bone sialoprotein,BSP ELISA Kit
YLA1179RA-48T 48T Ask for price

Rat bone sialoprotein,BSP ELISA Kit
YLA1179RA-96T 96T Ask for price

Human Bone sialoprotein 2 ELISA Kit
EK2726 96 tests
EUR 599

Human Bone Sialoprotein (BSP) CLIA Kit
20-abx492407
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Bone Sialoprotein (BSP) CLIA Kit
20-abx492408
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Bone Sialoprotein (BSP) CLIA Kit
abx196487-96tests 96 tests
EUR 990

Goat Bone Sialoprotein(BSP) ELISA Kit
NSL0981Gt 96T
EUR 528

Human Bone Sialoprotein (BSP) CLIA Kit
abx196487-100l 100 µl Ask for price

Human Bone Sialoprotein (BSP) CLIA Kit
abx196487-50l 50 µl
EUR 618.75

Human bone sialoprotein,BSP ELISA Kit
201-12-1493 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Bone Sialoprotein (BSP) ELISA Kit
DLR-BSP-Hu 96T
EUR 443
Description: serum, plasma, tissue homogenates or other biological fluids.

Human Bone Sialoprotein (BSP) ELISA Kit
DLR-BSP-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Bone Sialoprotein (BSP) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Bone Sialoprotein (BSP) ELISA Kit
DLR-BSP-Hu-96T 96T
EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Bone Sialoprotein (BSP) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Bone Sialoprotein (BSP) ELISA Kit
DLR-BSP-Mu 96T
EUR 454
Description: serum, plasma, tissue homogenates or other biological fluids.

Mouse Bone Sialoprotein (BSP) ELISA Kit
DLR-BSP-Mu-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Bone Sialoprotein (BSP) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Bone Sialoprotein (BSP) ELISA Kit
DLR-BSP-Mu-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Bone Sialoprotein (BSP) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse BSP(Bone Sialoprotein) ELISA Kit
ELK4422-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse BSP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse BSP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse BSP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse BSP in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse BSP(Bone Sialoprotein) ELISA Kit
ELK4422-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse BSP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse BSP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse BSP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse BSP in the samples is then determined by comparing the OD of the samples to the standard curve.

Human BSP(Bone Sialoprotein) ELISA Kit
ELK1761-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human BSP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human BSP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human BSP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human BSP in the samples is then determined by comparing the OD of the samples to the standard curve.

Human BSP(Bone Sialoprotein) ELISA Kit
ELK1761-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human BSP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human BSP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human BSP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human BSP in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse Bone sialoprotein ,BSP Elisa kit
EK732156 96 Wells
EUR 0.85

Human bone sialoprotein(BSP) Elisa Kit
EK700369 96 Wells
EUR 0.35

Calcium-containing SF hydrogels’ angiogenic potential investigated in an in ovo chick chorioallantoic membrane (CAM) assay, present a excessive quantity of converging blood vessels as in comparison with the unfavorable management, though no endothelial cells infiltration is noticed. The in vivo response evaluated in subcutaneous implantation in CD1 and nude NCD1 mice reveals that calcium-containing SF hydrogels are steady as much as 6 weeks after implantation. However, an elevated quantity of lifeless cells are additionally current in the surrounding tissue. The outcomes recommend the potential of calcium-containing SF hydrogels for use as novel in situ therapeutics for bone most cancers therapy functions, significantly to osteosarcoma.

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